HIV Unwrapped at New York Fashion Week was more than a runway show – it was an electric, standing-room-only moment of global solidarity, creativity, and hope. Presented through a partnership between ASHM and Plus Life Media, in collaboration with Gilead Sciences, the New York edition united cutting-edge HIV science with boundary-pushing design on one of the most influential fashion stages in the world. Working closely with Parsons School of Design, we identified and mentored emerging designers, each paired with HIV researchers, clinicians, and advocates, to reimagine the lab coat as a work of storytelling couture. The result was nine powerful, original New York designs – garments that embodied prevention breakthroughs, scientific innovation, lived experience, resilience, and activism. When those pieces took the runway – joined by designs from the Australian, UK, and Kigali editions – the show became a truly global celebration of progress and possibility. The energy in the room was palpable: joy, pride, tears, applause – and the unmistakable feeling that stigma was being dismantled in real time.
The impact rippled far beyond that night. HIV Unwrapped at New York Fashion Week became the centerpiece of a one-hour World AIDS Day television special documenting the journey from concept to catwalk – now streaming on Hulu and Disney+. The special captured the courage of the collaborators, the emotion behind every stitch, and the urgency driving the movement forward, earning a GLAAD Media Award nomination for Outstanding TV Journalism – Long-Form. With 554,744,710 total outlet UVM/impressions and sweeping press coverage across Variety, ABC, Plus Magazine, POZ Magazine, Queerty, OUT, GLAAD, and more, the New York edition ignited conversations around the world. What unfolded on that runway was not just fashion; it was visibility. It was validation. It was science stepping confidently into culture’s spotlight – and an at-capacity audience rising to its feet in celebration of how far we’ve come, and how much further we can go together.



















